Concurrence of both endometrialadenocarcinoma and ovarian adult granulosacelltumor (aGCT) is believed to be related to high estrogen milieu, but genomic alterations of the concurrentendometrialadenocarcinoma and aGCT are not known. For this, we analyzed an uterine endometrialadenocarcinoma and an ovarian aGCT in a same patient by a targetednext generationsequencing (NGS). We found a germline mutation in STK11 (p.L113fs). The endometrialadenocarcinoma harbored FGFR2 and TP53 mutations and the aGCT harbored a FOXL2 (p.C134 W) mutation. These germline and somatic mutations have been reported in non-concurrent tumors. These two tumors harbored 20 CNAs but only one CNA was exactly overlapped in the tumors. Our findings indicate that the concurrentendometrialadenocarcinoma and aGCT in this patient might not be genetically related to each other at germline or somatic level and suggest that such concurrence might be originated from non-genetic backgrounds including stimulated estrogen milieu.