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발표논문
Array-based comparative genomic hybridization and copy number variation in cancer research
작성자
pmrc
작성일
2018-05-16 21:12
조회
274
Cho, E. K., Tchinda, J., Freeman, J. L., Chung, Y. J., Cai, W. W., & Lee, C. (2006). Array-based comparative genomic hybridization and copy number variation in cancer research. Cytogenetic and genome research, 115(3-4), 262-272.
IF(2014) : 1.561
Abstract
Array-based comparative genomic hybridization (aCGH) is a molecular cytogenetic technique used in detecting and mapping DNA copy number alterations. aCGH is able to interrogate the entire genome at a previously unattainable, high resolution and has directly led to the recent appreciation of a novel class of genomic variation: copy number variation (CNV) in mammalian genomes. All forms of DNA variation/polymorphism are important for studying the basis of phenotypic diversity among individuals. CNV research is still at its infancy, requiring careful collation and annotation of accumulating CNV data that will undoubtedly be useful for accurate interpretation of genomic imbalances identified during cancer research.
IF(2014) : 1.561
Abstract
Array-based comparative genomic hybridization (aCGH) is a molecular cytogenetic technique used in detecting and mapping DNA copy number alterations. aCGH is able to interrogate the entire genome at a previously unattainable, high resolution and has directly led to the recent appreciation of a novel class of genomic variation: copy number variation (CNV) in mammalian genomes. All forms of DNA variation/polymorphism are important for studying the basis of phenotypic diversity among individuals. CNV research is still at its infancy, requiring careful collation and annotation of accumulating CNV data that will undoubtedly be useful for accurate interpretation of genomic imbalances identified during cancer research.